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Reconstruction of gene regulatory networks reveals chromatin remodelers and key transcription factors in tumorigenesis

BACKGROUND: Alterations in genetic and epigenetic landscapes are known to contribute to the development of different types of cancer. However, the mechanistic links between transcription factors and the epigenome which coordinate the deregulation of gene networks during cell transformation are large...

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Detalhes bibliográficos
Publicado no:Genome Med
Main Authors: Malysheva, Valeriya, Mendoza-Parra, Marco Antonio, Saleem, Mohamed-Ashick M., Gronemeyer, Hinrich
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872343/
https://ncbi.nlm.nih.gov/pubmed/27198694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-016-0310-3
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