Early life overfeeding impairs spatial memory performance by reducing microglial sensitivity to learning

BACKGROUND: Obesity can lead to cognitive dysfunction including poor performance in memory tasks. However, poor memory is not seen in all obese humans and takes several months to develop in animal models, indicating the adult brain is relatively resistant to obesity’s cognitive effects. We have seen...

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Publicado en:J Neuroinflammation
Autores principales: De Luca, Simone N., Ziko, Ilvana, Sominsky, Luba, Nguyen, Jason C. D., Dinan, Tara, Miller, Alyson A., Jenkins, Trisha A., Spencer, Sarah J.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872342/
https://ncbi.nlm.nih.gov/pubmed/27193330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0578-7
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