Frequency of Germline Mutations in 25 Cancer Susceptibility Genes in a Sequential Series of Patients With Breast Cancer

PURPOSE: Testing for germline mutations in BRCA1/2 is standard for select patients with breast cancer to guide clinical management. Next-generation sequencing (NGS) allows testing for mutations in additional breast cancer predisposition genes. The frequency of germline mutations detected by using NG...

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Bibliografiset tiedot
Julkaisussa:J Clin Oncol
Päätekijät: Tung, Nadine, Lin, Nancy U., Kidd, John, Allen, Brian A., Singh, Nanda, Wenstrup, Richard J., Hartman, Anne-Renee, Winer, Eric P., Garber, Judy E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Clinical Oncology 2016
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ORIGINAL REPORTS
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872307/
https://ncbi.nlm.nih.gov/pubmed/26976419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2015.65.0747
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