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TNFα promotes CAR-dependent migration of leukocytes across epithelial monolayers

Trans-epithelial migration (TEpM) of leukocytes during inflammation requires engagement with receptors expressed on the basolateral surface of the epithelium. One such receptor is Coxsackie and Adenovirus Receptor (CAR) that binds to Junctional Adhesion Molecule-like (JAM-L) expressed on leukocytes....

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Morton, Penny E., Hicks, Alexander, Ortiz-Zapater, Elena, Raghavan, Swetavalli, Pike, Rosemary, Noble, Alistair, Woodfin, Abigail, Jenkins, Gisli, Rayner, Emma, Santis, George, Parsons, Maddy
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872059/
https://ncbi.nlm.nih.gov/pubmed/27193388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26321
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