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Colonic tolerance develops in the iliac lymph nodes and can be established independent of CD103(+) dendritic cells

Tolerance to harmless exogenous antigens is the default immune response in the gastrointestinal tract. Although extensive studies have demonstrated the importance of the mesenteric lymph nodes (MLN) and intestinal CD103(+) dendritic cells (DCs) in driving small intestinal tolerance to protein antige...

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Detalhes bibliográficos
Publicado no:Mucosal Immunol
Main Authors: Veenbergen, Sharon, van Berkel, Lisette A, du Pré, M Fleur, He, JianPing, Karrich, Julien J, Costes, Léa MM, Luk, Franka, Simons-Oosterhuis, Ytje, Raatgeep, Rolien HC, Cerovic, Vuk, Cupedo, Tom, McI Mowat, Allan, Kelsall, Brian L, Samsom, Janneke N
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4871788/
https://ncbi.nlm.nih.gov/pubmed/26577569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2015.118
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