Longitudinal Changes in the Motor Learning-Related Brain Activation Response in Presymptomatic Huntington's Disease

Neurocognitive decline, including deficits in motor learning, occurs in the presymptomatic phase of Huntington’s disease (HD) and precedes the onset of motor symptoms. Findings from recent neuroimaging studies have linked these deficits to alterations in fronto-striatal and fronto-parietal brain net...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Holtbernd, Florian, Tang, Chris C., Feigin, Andrew, Dhawan, Vijay, Ghilardi, Maria Felice, Paulsen, Jane S., Guttman, Mark, Eidelberg, David
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4871440/
https://ncbi.nlm.nih.gov/pubmed/27192167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0154742
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