The Commercial Antibodies Widely Used to Measure H3 K56 Acetylation Are Non-Specific in Human and Drosophila Cells

Much of our understanding of the function of histone post-translational modifications in metazoans is inferred from their genomic localization and / or extrapolated from yeast studies. For example, acetylation of histone H3 lysine 56 (H3 K56Ac) is assumed to be important for transcriptional regulati...

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Udgivet i:PLoS One
Main Authors: Pal, Sangita, Graves, Hillary, Ohsawa, Ryosuke, Huang, Ting-hsiang, Wang, Pingping, Harmacek, Laura, Tyler, Jessica
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4871326/
https://ncbi.nlm.nih.gov/pubmed/27187594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0155409
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