CHRONIC NEBIVOLOL TREATMENT SUPPRESSES ENDOTHELIN-1-MEDIATED VASOCONSTRICTOR TONE IN ADULTS WITH ELEVATED BLOOD PRESSURE

Endothelin-1 plays a major role in the pathophysiology of hypertension and its associated cardiovascular risk. We tested the hypothesis that chronic nebivolol treatment reduces ET-1-mediated vasoconstrictor tone in adult humans with elevated blood pressure. Furthermore, reducing endothelin-1 vasocon...

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Pubblicato in:Hypertension
Autori principali: Diehl, Kyle J., Stauffer, Brian L., Dow, Caitlin A., Bammert, Tyler D., Brunjes, Danielle L., Greiner, Jared J., DeSouza, Christopher A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4871319/
https://ncbi.nlm.nih.gov/pubmed/27113048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.115.06979
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