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Affinity regression predicts the recognition code of nucleic acid binding proteins

Predicting the affinity profiles of nucleic acid-binding proteins directly from the protein sequence is a major unsolved problem. We present a statistical approach for learning the recognition code of a family of transcription factors (TFs) or RNA-binding proteins (RBPs) from high-throughput binding...

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Detalles Bibliográficos
Publicado en:Nat Biotechnol
Autores principales: Pelossof, Raphael, Singh, Irtisha, Yang, Julie L., Weirauch, Matthew T., Hughes, Timothy R., Leslie, Christina S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4871164/
https://ncbi.nlm.nih.gov/pubmed/26571099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3343
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