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An attenuated virus vaccine appears safe to the central nervous system of rainbow trout (Oncorhynchus mykiss) after intranasal delivery

Nasal vaccines are very effective but the olfactory organ provides direct access of antigens to the brain. Infectious hematopoietic necrosis virus (IHNV) is known to cause high mortalities in salmonids. The purpose of this study is to evaluate the safety of a live attenuated IHNV nasal (I.N) vaccine...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Fish Shellfish Immunol
Egile Nagusiak: Larragoite, Erin T., Tacchi, Luca, LaPatra, Scott E., Salinas, Irene
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4871134/
https://ncbi.nlm.nih.gov/pubmed/26772477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fsi.2016.01.006
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