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Estrogen Regulation of Fetal Adrenal Cortical Zone-Specific Development in the Nonhuman Primate Impacts Adrenal Production of Androgen and Cortisol and Response to ACTH in Females in Adulthood

We showed that the volume of the fetal zone of the fetal adrenal gland and serum dehydroepiandrosterone sulfate (DHAS) levels at term were increased in baboons in which estradiol levels were suppressed by treatment with aromatase inhibitor 4,4-[1,2,3-triazol-1yl-methylene] bis-benzonitrite (letrozol...

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Bibliographic Details
Published in:Endocrinology
Main Authors: Pepe, Gerald J., Maniu, Adina, Aberdeen, Graham, Lynch, Terrie J., Albrecht, Eugene D.
Format: Artigo
Language:Inglês
Published: Endocrine Society 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4870886/
https://ncbi.nlm.nih.gov/pubmed/26990066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2015-2087
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