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Estrogen Regulation of Fetal Adrenal Cortical Zone-Specific Development in the Nonhuman Primate Impacts Adrenal Production of Androgen and Cortisol and Response to ACTH in Females in Adulthood

We showed that the volume of the fetal zone of the fetal adrenal gland and serum dehydroepiandrosterone sulfate (DHAS) levels at term were increased in baboons in which estradiol levels were suppressed by treatment with aromatase inhibitor 4,4-[1,2,3-triazol-1yl-methylene] bis-benzonitrite (letrozol...

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Pubblicato in:Endocrinology
Autori principali: Pepe, Gerald J., Maniu, Adina, Aberdeen, Graham, Lynch, Terrie J., Albrecht, Eugene D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4870886/
https://ncbi.nlm.nih.gov/pubmed/26990066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2015-2087
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