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A Human Variant of Glucose-Regulated Protein 94 That Inefficiently Supports IGF Production

IGFs are critical for normal intrauterine and childhood growth and sustaining health throughout life. We showed previously that the production of IGF-1 and IGF-2 requires interaction with the chaperone glucose-regulated protein 94 (GRP94) and that the amount of secreted IGFs is proportional to the G...

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Dettagli Bibliografici
Pubblicato in:Endocrinology
Autori principali: Marzec, Michal, Hawkes, Colin P., Eletto, Davide, Boyle, Sarah, Rosenfeld, Ron, Hwa, Vivian, Wit, Jan M., van Duyvenvoorde, Hermine A., Oostdijk, Wilma, Losekoot, Monique, Pedersen, Oluf, Yeap, Bu Beng, Flicker, Leon, Barzilai, Nir, Atzmon, Gil, Grimberg, Adda, Argon, Yair
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4870884/
https://ncbi.nlm.nih.gov/pubmed/26982636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2015-2058
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