Impaired CD8(+) T cell responses upon Toll-like receptor activation in common variable immunodeficiency

BACKGROUND: Infections caused by bacteria or viruses are frequent in common variable immunodeficiency (CVID) patients due to antibody deficiencies, which may be associated with altered T cell function. CVID patients are frequently in contact with pathogen-associated molecular patterns (PAMPs), leadi...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: de Lollo, Camila, de Moraes Vasconcelos, Dewton, da Silva Oliveira, Luanda Mara, de Oliveira Titz, Tiago, Carneiro-Sampaio, Magda, Jacob, Cristina Miuki Abe, da Silva Duarte, Alberto José, Sato, Maria Notomi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4870753/
https://ncbi.nlm.nih.gov/pubmed/27188997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-0900-2
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