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Ubisol-Q10 Prevents Glutamate-Induced Cell Death by Blocking Mitochondrial Fragmentation and Permeability Transition Pore Opening

Mitochondrial dysfunction and oxidative stress are the major events that lead to the formation of mitochondrial permeability transition pore (mPTP) during glutamate-induced cytotoxicity and cell death. Coenzyme Q10 (CoQ10) has widely been used for the treatment of mitochondrial disorders and neurode...

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Detalhes bibliográficos
Publicado no:Int J Biol Sci
Main Authors: Kumari, Santosh, Mehta, Suresh L, Milledge, Gaolin Z., Huang, Xinyu, Li, Haining, Li, P. Andy
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4870712/
https://ncbi.nlm.nih.gov/pubmed/27194946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.13589
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