Dimethyloxaloylglycine Promotes the Angiogenic Activity of Mesenchymal Stem Cells Derived from iPSCs via Activation of the PI3K/Akt Pathway for Bone Regeneration

The vascularization of tissue-engineered bone is a prerequisite step for the successful repair of bone defects. Hypoxia inducible factor-1α (HIF-1α) plays an essential role in angiogenesis-osteogenesis coupling during bone regeneration and can activate the expression of angiogenic factors in mesench...

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Bibliographic Details
Published in:Int J Biol Sci
Main Authors: Zhang, Jieyuan, Guan, Junjie, Qi, Xin, Ding, Hao, Yuan, Hong, Xie, Zongping, Chen, Chunyuan, Li, Xiaolin, Zhang, Changqing, Huang, Yigang
Format: Artigo
Language:Inglês
Published: Ivyspring International Publisher 2016
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4870708/
https://ncbi.nlm.nih.gov/pubmed/27194942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.14025
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