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Heat Shock Factor 1 Mediates Latent HIV Reactivation

HSF1, a conserved heat shock factor, has emerged as a key regulator of mammalian transcription in response to cellular metabolic status and stress. To our knowledge, it is not known whether HSF1 regulates viral transcription, particularly HIV-1 and its latent form. Here we reveal that HSF1 extensive...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Pan, Xiao-Yan, Zhao, Wei, Zeng, Xiao-Yun, Lin, Jian, Li, Min-Min, Shen, Xin-Tian, Liu, Shu-Wen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4870680/
https://ncbi.nlm.nih.gov/pubmed/27189267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26294
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