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Power Calculation of Multi-step Combined Principal Components with Applications to Genetic Association Studies

Principal component analysis (PCA) is a useful tool to identify important linear combination of correlated variables in multivariate analysis and has been applied to detect association between genetic variants and human complex diseases of interest. How to choose adequate number of principal compone...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Li, Zhengbang, Zhang, Wei, Pan, Dongdong, Li, Qizhai
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4870571/
https://ncbi.nlm.nih.gov/pubmed/27189724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26243
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