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Power Calculation of Multi-step Combined Principal Components with Applications to Genetic Association Studies

Principal component analysis (PCA) is a useful tool to identify important linear combination of correlated variables in multivariate analysis and has been applied to detect association between genetic variants and human complex diseases of interest. How to choose adequate number of principal compone...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Li, Zhengbang, Zhang, Wei, Pan, Dongdong, Li, Qizhai
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4870571/
https://ncbi.nlm.nih.gov/pubmed/27189724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26243
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