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Treatment with a GnRH receptor agonist, but not the GnRH receptor antagonist degarelix, induces atherosclerotic plaque instability in ApoE(−/−) mice

Androgen-deprivation therapy (ADT) for prostate cancer has been associated with increased risk for development of cardiovascular events and recent pooled analyses of randomized intervention trials suggest that this primarily is the case for patients with pre-existing cardiovascular disease treated w...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Knutsson, Anki, Hsiung, Sabrina, Celik, Selvi, Rattik, Sara, Mattisson, Ingrid Yao, Wigren, Maria, Scher, Howard I., Nilsson, Jan, Hultgårdh-Nilsson, Anna
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4870555/
https://ncbi.nlm.nih.gov/pubmed/27189011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26220
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