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Expressing Redundancy among Linear-Epitope Sequence Data Based on Residue-Level Physicochemical Similarity in the Context of Antigenic Cross-Reaction

Epitope-based design of vaccines, immunotherapeutics, and immunodiagnostics is complicated by structural changes that radically alter immunological outcomes. This is obscured by expressing redundancy among linear-epitope data as fractional sequence-alignment identity, which fails to account for pote...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Adv Bioinformatics
1. Verfasser: Caoili, Salvador Eugenio C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4870339/
https://ncbi.nlm.nih.gov/pubmed/27274725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/1276594
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