Improved Hemocompatibility of Silicone Rubber Extracorporeal Tubing via Solvent Swelling-Impregnation of S-Nitroso-N-acetylpenicillamine (SNAP) and Evaluation in Rabbit Thrombogenicity Model

Blood-contacting devices, including extracorporeal circulation (ECC) circuits, can suffer from complications due to platelet activation and thrombus formation. Development of nitric oxide (NO) releasing polymers is one method to improve hemocompatibility, taking advantage of the ability of low level...

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Bibliographic Details
Published in:Acta Biomater
Main Authors: Brisbois, Elizabeth J., Major, Terry C., Goudie, Marcus, Bartlett, Robert H., Meyerhoff, Mark E., Handa, Hitesh
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4870167/
https://ncbi.nlm.nih.gov/pubmed/27095484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2016.04.025
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