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NOD1/NOD2 signaling links ER stress with inflammation
Endoplasmic reticulum (ER) stress is a major contributor to inflammatory diseases, such as Crohn’s disease and type 2 diabetes(1,2). ER stress induces the unfolded protein response (UPR), which involves activation of three transmembrane receptors, ATF6 (activating transcription factor 6), PERK (prot...
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| Publicado no: | Nature |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4869892/ https://ncbi.nlm.nih.gov/pubmed/27007849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature17631 |
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