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USP7 is a SUMO deubiquitinase essential for DNA replication

Post-translational modification of proteins by ubiquitin (Ub) and Ub-like modifiers regulates various aspects of DNA replication. We previously showed that the chromatin around replisomes is rich in SUMO and depleted in Ub, whereas an opposite pattern is observed in mature chromatin. How this SUMO-r...

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Bibliographic Details
Published in:Nat Struct Mol Biol
Main Authors: Lecona, Emilio, Rodriguez-Acebes, Sara, Specks, Julia, Lopez-Contreras, Andres J, Ruppen, Isabel, Murga, Matilde, Muñoz, Javier, Mendez, Juan, Fernandez-Capetillo, Oscar
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4869841/
https://ncbi.nlm.nih.gov/pubmed/26950370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3185
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