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Targeting protein ubiquitylation: DDB1 takes its RING off
Ubiquitin E3 ligases of the RING and HECT families are distinct not only in their catalytic mechanisms but also in targeting substrates. Now it seems that one heterodimeric complex can target substrates to both types of E3 ligase.
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| Publicado no: | Nat Cell Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4869686/ https://ncbi.nlm.nih.gov/pubmed/19337321 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb0409-379 |
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