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Clinical developments in the treatment of relapsed or relapsed and refractory multiple myeloma: impact of panobinostat, the first-in-class histone deacetylase inhibitor

BACKGROUND: Panobinostat is a new agent for the treatment of relapsed and refractory multiple myeloma (rrMM) as part of a combination regimen. This article presents an overview of the mechanism of action, pharmacokinetics, safety, efficacy, patient care strategies, and role of the agent in treating...

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Vydáno v:Onco Targets Ther
Hlavní autoři: Redic, Kimberly A, Hough, Shannon M, Price, Erika M
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4869663/
https://ncbi.nlm.nih.gov/pubmed/27274274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S87962
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