RNA-Seq following PCR-based sorting reveals rare cell transcriptional signatures

BACKGROUND: Rare cell subtypes can profoundly impact the course of human health and disease, yet their presence within a sample is often missed with bulk molecular analysis. Single-cell analysis tools such as FACS, FISH-FC and single-cell barcode-based sequencing can investigate cellular heterogenei...

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Bibliografiske detaljer
Udgivet i:BMC Genomics
Main Authors: Pellegrino, Maurizio, Sciambi, Adam, Yates, Jamie L., Mast, Joshua D., Silver, Charles, Eastburn, Dennis J.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Methodology Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4869385/
https://ncbi.nlm.nih.gov/pubmed/27189161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-2694-2
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