Paracoccidioides brasiliensis infection promotes thymic disarrangement and premature egress of mature lymphocytes expressing prohibitive TCRs

BACKGROUND: Paracoccidioidomycosis, a chronic granulomatous fungal disease caused by Paracoccidioides brasiliensis yeast cells affects mainly rural workers, albeit recently cases in immunosuppressed individuals has been reported. Protective immune response against P. brasiliensis is dependent on the...

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Publicado en:BMC Infect Dis
Autores principales: Di Gangi, Rosaria, Alves da Costa, Thiago, Thomé, Rodolfo, Peron, Gabriela, Burger, Eva, Verinaud, Liana
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2016
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4869377/
https://ncbi.nlm.nih.gov/pubmed/27189089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12879-016-1561-8
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