The pharmacokinetics of mianserin suppositories for rectal administration in dogs and healthy volunteers: a pilot study

BACKGROUND: We formulated mianserin suppositories for the treatment of delirium and evaluated their pharmacokinetics by measuring plasma drug concentrations in dogs and healthy human volunteers. METHODS: Mianserin suppositories were prepared by a melting technique using Tetramide® tablets and Witeps...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Pharm Health Care Sci
Auteurs principaux: Nawata, Shuichi, Kohyama, Noriko, Uchida, Naoki, Numazawa, Satoshi, Ohbayashi, Masayuki, Kobayashi, Yasuna, Iwata, Masanori, Nakajima, Takanori, Saito, Hiroshi, Izuka, Akira, Yamamoto, Toshinori
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4869351/
https://ncbi.nlm.nih.gov/pubmed/27190632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40780-016-0046-7
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