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Can abscopal effects of local radiotherapy be predicted by modeling T cell trafficking?

The abscopal effect of radiation describes tumor regression in metastases outside of the field upon treatment of one site, and is mediated by radiation-induced anti-tumor T cells. The ability of radiation to generate an in situ tumor vaccine and improve responses to immunotherapy is under intense in...

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Библиографические подробности
Опубликовано в: :J Immunother Cancer
Главные авторы: Demaria, Sandra, Formenti, Silvia C.
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4869282/
https://ncbi.nlm.nih.gov/pubmed/27190630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-016-0133-1
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