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Selective forces and mutational biases drive stop codon usage in the human genome: a comparison with sense codon usage

BACKGROUND: The three stop codons UAA, UAG, and UGA signal the termination of mRNA translation. As a result of a mechanism that is not adequately understood, they are normally used with unequal frequencies. RESULTS: In this work, we showed that selective forces and mutational biases drive stop codon...

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Publicat a:BMC Genomics
Autor principal: Trotta, Edoardo
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4869280/
https://ncbi.nlm.nih.gov/pubmed/27188984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-2692-4
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