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Heterogeneity and clinical significance of ESR1 mutations in ER-positive metastatic breast cancer patients receiving fulvestrant
Mutations in ESR1 have been associated with resistance to aromatase inhibitor (AI) therapy in patients with ER+ metastatic breast cancer. Little is known of the impact of these mutations in patients receiving selective oestrogen receptor degrader (SERD) therapy. In this study, hotspot mutations in E...
Zapisane w:
Wydane w: | Nat Commun |
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Główni autorzy: | , , , , , , , , , , , , , , , |
Format: | Artigo |
Język: | Inglês |
Wydane: |
Nature Publishing Group
2016
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Hasła przedmiotowe: | |
Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4869259/ https://ncbi.nlm.nih.gov/pubmed/27174596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11579 |
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