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Symmetric spike timing-dependent plasticity at CA3–CA3 synapses optimizes storage and recall in autoassociative networks

CA3–CA3 recurrent excitatory synapses are thought to play a key role in memory storage and pattern completion. Whether the plasticity properties of these synapses are consistent with their proposed network functions remains unclear. Here, we examine the properties of spike timing-dependent plasticit...

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Publicat a:Nat Commun
Autors principals: Mishra, Rajiv K., Kim, Sooyun, Guzman, Segundo J., Jonas, Peter
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4869174/
https://ncbi.nlm.nih.gov/pubmed/27174042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11552
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