Essential Contributions of Serotonin Transporter Inhibition to the Acute and Chronic Actions of Fluoxetine and Citalopram in the SERT Met172 Mouse

Depression is a common mental illness and a leading cause of disability. The most widely prescribed antidepressant medications are serotonin (5-HT) selective reuptake inhibitors (SSRIs). Although there is much support for 5-HT transporter (SERT) antagonism as a basis of antidepressant efficacy, this...

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Bibliographische Detailangaben
Veröffentlicht in:Neuropsychopharmacology
Hauptverfasser: Nackenoff, Alex G, Moussa-Tooks, Alexandra B, McMeekin, Austin M, Veenstra-VanderWeele, Jeremy, Blakely, Randy D
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4869040/
https://ncbi.nlm.nih.gov/pubmed/26514584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2015.335
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