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Defective excitation-contraction coupling is partially responsible for impaired contractility in hindlimb muscles of Stac3 knockout mice

The Stac3 gene is exclusively expressed in skeletal muscle, and Stac3 knockout is perinatal lethal in mice. Previous data from Stac3-deleted diaphragms indicated that Stac3-deleted skeletal muscle could not contract because of defective excitation-contraction (EC) coupling. In this study, we determi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Cong, Xiaofei, Doering, Jonathan, Grange, Robert W., Jiang, Honglin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868984/
https://ncbi.nlm.nih.gov/pubmed/27184118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26194
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