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The mitochondrial outer membrane protein MDI promotes local protein synthesis and mtDNA replication

Early embryonic development features rapid nuclear DNA replication cycles, but lacks mtDNA replication. To meet the high‐energy demands of embryogenesis, mature oocytes are furnished with vast amounts of mitochondria and mtDNA. However, the cellular machinery driving massive mtDNA replication in ova...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Zhang, Yi, Chen, Yong, Gucek, Marjan, Xu, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868955/
https://ncbi.nlm.nih.gov/pubmed/27053724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201592994
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