BRAF Mutation (V600E) Prevalence in Mexican Patients Diagnosed with Melanoma

BACKGROUND: B-Raf is a serine/threonine protein kinase activating the MAP kinase/ERK-signaling pathway. It has been shown that 50% of melanomas harbor activating BRAF mutations, with over 90% being the V600E mutation. OBJECTIVE: The goal of this research was to determine the prevalence of the BRAF V...

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Udgivet i:Case Rep Oncol
Main Authors: Zepeda-Lopez, Priscilla Denise, Salas-Alanis, Julio Cesar, Toussaint-Caire, Sonia, Gutierrez-Mendoza, Daniela, Vega-Memije, Elisa, Silva, Saúl Lino, Fajardo-Ramírez, Oscar Raul, Alcazar, Gregorio, Moreno-Treviño, María Guadalupe, Saldaña, Hugo Alberto Barrera
Format: Artigo
Sprog:Inglês
Udgivet: S. Karger AG 2016
Fag:
Published online: April, 2016
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868925/
https://ncbi.nlm.nih.gov/pubmed/27194985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000445939
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