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BRAF Mutation (V600E) Prevalence in Mexican Patients Diagnosed with Melanoma
BACKGROUND: B-Raf is a serine/threonine protein kinase activating the MAP kinase/ERK-signaling pathway. It has been shown that 50% of melanomas harbor activating BRAF mutations, with over 90% being the V600E mutation. OBJECTIVE: The goal of this research was to determine the prevalence of the BRAF V...
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| Опубликовано в: : | Case Rep Oncol |
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| Главные авторы: | , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
S. Karger AG
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4868925/ https://ncbi.nlm.nih.gov/pubmed/27194985 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000445939 |
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