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Oncogenic KRAS Regulates Tumor Cell Signaling via Stromal Reciprocation
Oncogenic mutations regulate signaling within both tumor cells and adjacent stromal cells. Here, we show that oncogenic KRAS (KRAS(G12D)) also regulates tumor cell signaling via stromal cells. By combining cell-specific proteome labeling with multivariate phosphoproteomics, we analyzed heterocellula...
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Publicado no: | Cell |
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Main Authors: | , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Cell Press
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4868820/ https://ncbi.nlm.nih.gov/pubmed/27087446 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.03.029 |
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