The Receptor for Advanced Glycation Endproducts (RAGE) Activates the AIM2 Inflammasome in Acute Pancreatitis

Severe acute pancreatitis (AP) is responsible for significant human morbidity and mortality worldwide. Currently, no specific treatments for AP exist, primarily due to the lack of a mechanistic understanding of sterile inflammation and the resultant multisystem organ dysfunction, the pathologic resp...

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Pubblicato in:J Immunol
Autori principali: Kang, Rui, Chen, Ruochan, Xie, Min, Cao, Lizhi, Lotze, Michael T., Tang, Daolin, Zeh, Herbert J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868774/
https://ncbi.nlm.nih.gov/pubmed/27045109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502340
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