MiR-let-7a inhibits cell proliferation, migration, and invasion by down-regulating PKM2 in gastric cancer

In contrast to normal differentiated cells that depend on aerobicoxidation for energy production, cancer cells use aerobic glycolysis as the main source (Warburg's effect). The M2 splice isoform of pyruvate kinase (PKM2) is the key regulator for the aerobic glycolysis, high expression of PKM2 c...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Tang, Ran, Yang, Chao, Ma, Xiang, Wang, Younan, Luo, Dakui, Huang, Chi, Xu, Zekuan, Liu, Ping, Yang, Li
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868734/
https://ncbi.nlm.nih.gov/pubmed/26745603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6821
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