LKB1 acts as a critical gatekeeper of ovarian primordial follicle pool

Liver Kinase b1 (LKB1/STK11)is a tumor suppressor responsible for the Peutz-Jeghers syndrome, an autosomal-dominant, cancer-prone disorder in which patients develop neoplasms in several organs, including the oviduct, ovary, and cervix. Besides, the C allele of a SNP in the Lkb1 gene impedes the like...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Jiang, Zong-Zhe, Hu, Meng-Wen, Ma, Xue-Shan, Schatten, Heide, Fan, Heng-Yu, Wang, Zhen-Bo, Sun, Qing-Yuan
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868718/
https://ncbi.nlm.nih.gov/pubmed/26745759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6792
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