Targeting the Warburg effect in cancer cells through ENO1 knockdown rescues oxidative phosphorylation and induces growth arrest

In the last 5 years, novel knowledge on tumor metabolism has been revealed with the identification of critical factors that fuel tumors. Alpha-enolase (ENO1) is commonly over-expressed in tumors and is a clinically relevant candidate molecular target for immunotherapy. Here, we silenced ENO1 in huma...

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Udgivet i:Oncotarget
Main Authors: Capello, Michela, Ferri-Borgogno, Sammy, Riganti, Chiara, Chattaragada, Michelle Samuel, Principe, Moitza, Roux, Cecilia, Zhou, Weidong, Petricoin, Emanuel F., Cappello, Paola, Novelli, Francesco
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2015
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868708/
https://ncbi.nlm.nih.gov/pubmed/26734996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6798
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