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A novel approach to the discovery of anti-tumor pharmaceuticals: searching for activators of liponecrosis
A recently conducted chemical genetic screen for pharmaceuticals that can extend longevity of the yeast Saccharomyces cerevisiae has identified lithocholic acid as a potent anti-aging molecule. It was found that this hydrophobic bile acid is also a selective anti-tumor chemical compound; it kills di...
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| Published in: | Oncotarget |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Impact Journals LLC
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4868681/ https://ncbi.nlm.nih.gov/pubmed/26636650 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6440 |
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