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Use of biotelemetry to define physiology-based deterioration thresholds in a murine cecal ligation and puncture model of sepsis
OBJECTIVE: Murine models of critical illness are commonly used to test new therapeutic interventions. However, these interventions are often administered at fixed time intervals after the insult, perhaps ignoring the inherent variability in magnitude and temporality of the host response. We propose...
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Publicado no: | Crit Care Med |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4868666/ https://ncbi.nlm.nih.gov/pubmed/26862708 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0000000000001615 |
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