Investigating and Targeting Chronic Lymphocytic Leukemia Metabolism with the HIV Protease Inhibitor Ritonavir and Metformin

Chronic Lymphocytic Leukemia (CLL) remains fatal due to the development of resistance to existing therapies. Targeting abnormal glucose metabolism sensitizes various cancer cells to chemotherapy and/or elicits toxicity. Examination of glucose dependency in CLL demonstrated variable sensitivity to gl...

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Bibliographic Details
Published in:Leuk Lymphoma
Main Authors: Adekola, Kehinde U.A., Aydemir, Sevim D., Ma, Shuo, Zhou, Zheng, Rosen, Steven T., Shanmugam, Mala
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868500/
https://ncbi.nlm.nih.gov/pubmed/24828872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10428194.2014.922180
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