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Absolute requirement for GTP in activation of human neutrophil NADPH oxidase in a cell-free system: role of ATP in regenerating GTP.

Guanine and/or adenine nucleotides appear to be involved in the activation of the superoxide-generating NADPH oxidase of phagocytic cells. Their precise roles, however, are unclear, as much of the evidence for their involvement comes from experiments in which nucleotides have been added to complex s...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Peveri, P, Heyworth, P G, Curnutte, J T
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1992
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48685/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1312725/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.6.2494
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