Retinal neurodegeneration may precede microvascular changes characteristic of diabetic retinopathy in diabetes mellitus

Diabetic retinopathy (DR) has long been recognized as a microvasculopathy, but retinal diabetic neuropathy (RDN), characterized by inner retinal neurodegeneration, also occurs in people with diabetes mellitus (DM). We report that in 45 people with DM and no to minimal DR there was significant, progr...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Sohn, Elliott H., van Dijk, Hille W., Jiao, Chunhua, Kok, Pauline H. B., Jeong, Woojin, Demirkaya, Nazli, Garmager, Allison, Wit, Ferdinand, Kucukevcilioglu, Murat, van Velthoven, Mirjam E. J., DeVries, J. Hans, Mullins, Robert F., Kuehn, Markus H., Schlingemann, Reinier Otto, Sonka, Milan, Verbraak, Frank D., Abràmoff, Michael David
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2016
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PNAS Plus
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868487/
https://ncbi.nlm.nih.gov/pubmed/27114552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1522014113
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