α/β-Hydrolase domain-containing 6 (ABHD6) negatively regulates the surface delivery and synaptic function of AMPA receptors

In the brain, AMPA-type glutamate receptors are major postsynaptic receptors at excitatory synapses that mediate fast neurotransmission and synaptic plasticity. α/β-Hydrolase domain-containing 6 (ABHD6), a monoacylglycerol lipase, was previously found to be a component of AMPA receptor macromolecula...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Wei, Mengping, Zhang, Jian, Jia, Moye, Yang, Chaojuan, Pan, Yunlong, Li, Shuaiqi, Luo, Yiwen, Zheng, Junyuan, Ji, Jianguo, Chen, Jianguo, Hu, Xinli, Xiong, Jingwei, Shi, Yun, Zhang, Chen
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2016
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PNAS Plus
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868484/
https://ncbi.nlm.nih.gov/pubmed/27114538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1524589113
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