Comparison of syncytiotrophoblast generated from human embryonic stem cells and from term placentas

Human embryonic stem cells (ESCs) readily commit to the trophoblast lineage after exposure to bone morphogenetic protein-4 (BMP-4) and two small compounds, an activin A signaling inhibitor and a FGF2 signaling inhibitor (BMP4/A83-01/PD173074; BAP treatment). During differentiation, areas emerge with...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Yabe, Shinichiro, Alexenko, Andrei P., Amita, Mitsuyoshi, Yang, Ying, Schust, Danny J., Sadovsky, Yoel, Ezashi, Toshihiko, Roberts, R. Michael
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2016
Pynciau:
PNAS Plus
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868474/
https://ncbi.nlm.nih.gov/pubmed/27051068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1601630113
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