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Targeting lymphoma with precision using semisynthetic anti-idiotype peptibodies

B-cell lymphomas express a functionally active and truly tumor-specific cell-surface product, the variable region of the B-cell receptor (BCR), otherwise known as idiotype. The tumor idiotype differs, however, from patient to patient, making it a technical challenge to exploit for therapy. We have d...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Torchia, James, Weiskopf, Kipp, Levy, Ronald
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868466/
https://ncbi.nlm.nih.gov/pubmed/27114517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1603335113
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