HIV-1 Vpr degrades the HLTF DNA translocase in T cells and macrophages

Viruses often interfere with the DNA damage response to better replicate in their hosts. The human immunodeficiency virus 1 (HIV-1) viral protein R (Vpr) protein has been reported to modulate the activity of the DNA repair structure-specific endonuclease subunit (SLX4) complex and to promote cell cy...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Lahouassa, Hichem, Blondot, Marie-Lise, Chauveau, Lise, Chougui, Ghina, Morel, Marina, Leduc, Marjorie, Guillonneau, François, Ramirez, Bertha Cecilia, Schwartz, Olivier, Margottin-Goguet, Florence
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868422/
https://ncbi.nlm.nih.gov/pubmed/27114546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1600485113
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